International Journal of Pain (IJP) reviews all manuscripts received. A manuscript is first reviewed for its format and adherence to the aims and scope of the journal. If the manuscript meets these two criteria, it is checked for plagiarism or duplicate publication with Similarity Check. After confirming its result, it is sent to two (or more) relevant investigators available for review of the contents. The editor selects peer referees by recommendation of editorial board members or from the board's specialist database.

IJP adopts a double-blind review, which means that the reviewers and authors cannot identify each other's information. The authors' names and affiliations are removed during peer review. Assuming the manuscript is sent to reviewers, IJP waits to receive opinions from at least two reviewers. In addition, if deemed necessary, a review of statistics may be required. The acceptance criteria for all papers are based on the quality and originality of the research and its scientific significance. Acceptance of a manuscript is decided based on the critiques and recommended decisions of the reviewers.

An initial decision is normally made within 4 weeks of receipt of a manuscript, and the reviewers' comments are sent to the corresponding author by e-mail. The corresponding author must indicate the alterations that have been made in response to the reviewers’ comments item by item. A final decision on acceptance/rejection for publication is forwarded to the corresponding author from the editor.